Advancing the Frontier of Metabolic Research
Retatrutide — the first triple hormone receptor agonist targeting GLP-1, GIP, and Glucagon simultaneously. Engineered for researchers who refuse to compromise on purity.
24.2%
Mean mass reduction at 48 weeks
≥99%
Guaranteed peptide purity
3x
Hormone receptor targets
MECHANISM OF ACTION
The Triple Pathway
While predecessors act on one or two receptors, Retatrutide co-activates three
distinct hormone pathways — delivering compounding synergistic effects
unmatched in current research models.
01
GLP-1
APPETITE & DIGESTION
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
02
GIP
INSULIN RESPONSE
Glucose-dependent insulinotropic polypeptide activation potentiates insulin secretion and promotes lipid utilisation from adipose tissue.
03
Glycagon
ENERGY EXPENDITURE
Glucagon receptor co-agonism elevates basal metabolic rate and drives hepatic fat oxidation, compounding the dual-agonist effect.
Triple-Action Synergy
UNMATCHED IN CURRENT RESEARCH
No other compound in active clinical study simultaneously engages three distinct metabolic hormone receptors at therapeutic research concentrations.
GLP-1 Active | GIP Active | Glucagon Active
INDUSTRY PROBLEM
Compromised Peptides
Ruin Research
Most vendors ship pre-reconstituted peptides with degraded purity, absent cold-chain, and substandard solvents. The result: compounds that invalidate your data before the experiment begins.
No Bacteriostatic Water
Many vendors use plain sterile water instead of 0.9% benzyl alcohol solution, causing rapid bacterial contamination and single-use shelf life.
Transit Agitation
Physical shaking during postal transit breaks delicate amino acid bonds in pre-reconstituted peptides before they reach the laboratory.
Cold-Chain Failure
Temperature fluctuations from absent cold-chain logistics accelerate degradation, delivering a measurably weakened compound.
Purity Compromise
Sub-95% purity introduces truncated synthesis sequences and oxidised variants that confound cellular assays and invalidate readouts.
THE RETANOVA STANDARD
Uncompromising Purity
& Logistics
Just-in-Time Reconstitution
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
Bacteriostatic Water (0.9% BnOH)
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
Temperature- Controlled Transport
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
Third-Party BatchTesting
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
Verified COAs Provided
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
UV-Resistant Packaging
Glucagon-like peptide-1 receptor activation suppresses appetite and slows gastric emptying, reducing caloric intake in testing models.
STORAGE & HANDLING
Protocol for
Molecular Integrity
Proper storage is the final step in a quality-first supply
chain. Deviation from these protocols will degrade the
compound and invalidate your experimental data.
Lyophilised Vials (Powder)
Below −18°C
Strictly protected from direct light at all times.
Reconstituted Solution (Liquid)
2–8°C
Refrigerate immediately after reconstitution.
Freeze-Thaw Cycles
Avoid entirely
Repeated cycling irreparably damages peptide structure.
ELEVATE YOUR RESEARCH
Trust Your Data to the
Highest-Purity Peptides
Batch-tested, cold-chain shipped, and reconstituted just-in-time.
Every order backed by a verified Certificate of Analysis.
STORAGE & HANDLING
Step-by-Step Instructions
For researchers using 20mg, 30mg, or 40mg Retatrutide lyophilized powder vials and provided bacteriostatic water.
STEP 1 of 7
Bring vials to room temperature
Take the Retatrutide peptide vial and bacteriostatic water vial out of the fridge 10–15 minutes before use. Allow them to reach room temperature.
STEP 2 of 7
Sanitize the vials
Pop off the protective plastic caps. Wipe the rubber stoppers of both vials with a fresh alcohol swab. Allow them to air dry. Do not blow on them.
STEP 3 of 7
Extract bacteriostatic water
Uncap a sterile mixing syringe. Pull back the plunger to draw air equal to the volume of bacteriostatic water you need. Inject the air into the vial, then invert the vial and slowly draw out the exact volume of water required.
STEP 4 of 7
Reconstitute the peptide
Pierce the centre of the lyophilized peptide vial. Do not spray the water directly onto the powder. Slowly angle the needle so the bacteriostatic water drips down the inside glass wall.
STEP 5 of 7
Dissolve and inspect
Once all water is added, remove the syringe. Gently swirl or roll the vial between your fingers until the powder is completely dissolved. Never shake the vial.
STEP 6 of 7
Draw the precise dose
Using a new, sterile insulin syringe, pull back the plunger to draw air equal to your required dose. Inject the air into the vial, invert, and slowly pull back to your required unit mark. Gently tap the syringe to clear any air bubbles and push them back into the vial.
STEP 7 of 7
Dispense and refrigerate
Withdraw the needle and administer the dose to your test medium. Press the plunger fully and hold for 3–5 seconds. Dispose of the syringe in a sharps container immediately. Return the reconstituted peptide vial to the refrigerator (2–8°C) upright.
For researchers using 20mg, 30mg, or 40mg pre-filled Retatrutide pens.
STEP 1 of 7
Bring the pen to room temperature
Take the pen out of the fridge 10–15 minutes before use. Cold solution is thicker and dispenses less accurately. Never microwave, warm in hot water, or shake the pen.
STEP 2 of 7
Inspect the cartridge
STEP 3 of 7
Attach a fresh needle
Use a new 31G 6mm needle every time. Wipe the rubber septum with an alcohol swab, then screw on a new needle. Reused needles become blunt, introduce contamination, and cause dose loss.
STEP 4 of 7
Prime the needle (Normally Redundant)
Our pens are fully primed, with all air bubbles removed before shipping. Therefore, this step should not be needed.Note box in the image – “If you wish to confirm:” Dial 2 units, point the needle upwards, and press the plunger until a droplet appears at the tip. If no droplet appears, contact us.
STEP 5 of 7
Dial the dose in clicks
Refer to your pen and clicks-per-mg card. Each click equals a fixed volume, and the mg-per-click depends on the vial strength and fill volume. How many clicks equate to a 1mg dose will be printed directly on the pen. Use this alongside the calibrated card included in your box.
STEP 6 of 7
Dispense and hold
Press the plunger fully and hold it in place for 6–10 seconds so the full dialled volume is delivered, rather than being left inside the needle.
STEP 7 of 7
Remove the needle and refrigerate
Never store the pen with a needle attached. Unscrew and dispose of the needle in a designated sharps bin. Storing the pen without a needle prevents solution leaks and stops air from entering the cartridge. Return the pen to 2–8°C.
GET IN TOUCH
Questions About Your Order or Research?
Our team is here to help with product details, batch documentation, shipping, and Certificate of Analysis requests. Reach out and we’ll respond as quickly as possible.